American stand-up comedian, actor, and author, David Brenner, has died at the age of 59 after fighting cancer for years.

Brenner is popularly known for “The Tonight Show”, his national television debut, which starred Johnny Carson.

Brenner, after fighting cancer, died peacefully at his home in New York City with his family at his side.

His 150-plus “Tonight Show” appearances turned the former documentary filmmaker into a hot comedian.

Brenner was a regular on other TV talk shows and game shows and starred in four HBO comedy specials.

He moved with the times, trading routines about the humor of everyday life for jokes about social and political issues. He appeared on MSNBC and Fox News Channel cable programs as well as talk shows.

Brenner worked steadily through 2013 doing standup. He had a four-day gig last December which included a New Year’s Eve show at a King of Prussia, Pa., casino-resort in which he showcased young comedians.